abstract：OBJECTIVE:To determine the prevalence of nephrogenic systemic fibrosis (NSF) in patients with chronic kidney disease (CKD) who have received gadopentetate dimeglumine. MATERIALS AND METHODS:We retrospectively studied all patients who underwent contrast-enhanced magnetic resonance imagings (CE-MRIs) between January 1, ...

journal_title：Investigative radiology

authors： Hope TA,Herfkens RJ,Denianke KS,LeBoit PE,Hung YY,Weil E

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:To evaluate the dependency of tumor contrast enhancement (CE) in regard to protein-binding properties of contrast agents, using 4 different agents with a wide range of protein-binding capacities in a standardized rat brain glioma model. MATERIAL AND METHODS:Sixteen rats with implanted brain gliomas were evalua...

journal_title：Investigative radiology

authors： Wintersperger BJ,Runge VM,Tweedle MF,Jackson CB,Reiser MF

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Commercially available iodinated contrast media (CM) show significantly different physico-chemical properties. The relevance of the viscosity of CM may be underestimated as a contributing factor for clinically relevant renal failure as suggested by a large registry data analysis (Swedish registry study). The ...

journal_title：Investigative radiology

authors： Jost G,Pietsch H,Sommer J,Sandner P,Lengsfeld P,Seidensticker P,Lehr S,Hütter J,Sieber MA

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the influence of different weighting factors on contrast enhancement, signal-to-noise ratio (SNR), and image quality in image fusion in dual energy computed tomography (DECT) angiography. MATERIAL AND METHODS:Fifteen patients underwent a CT angiography of the aorta with ...

journal_title：Investigative radiology

authors： Behrendt FF,Schmidt B,Plumhans C,Keil S,Woodruff SG,Ackermann D,Mühlenbruch G,Flohr T,Günther RW,Mahnken AH

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Thermal dose in tumor tissue is a key factor for regional hyperthermia (HT) combined with chemotherapy and for drug delivery using thermosensitive liposomes (TSL). It influences therapy outcome, affects the accumulation of liposomes, and triggers the content release from TSL in the target tissue. For the dev...

journal_title：Investigative radiology

authors： Peller M,Schwerdt A,Hossann M,Reinl HM,Wang T,Sourbron S,Ogris M,Lindner LH

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:With the introduction of ultrashort echo time (UTE) sequences solid polymeric materials might become visible on clinical whole-body magnetic resonance (MR) scanners. The aim of this study was to characterize solid polymeric materials typically used for instruments in magnetic resonance guided interventions an...

journal_title：Investigative radiology

authors： Springer F,Martirosian P,Schwenzer NF,Szimtenings M,Kreisler P,Claussen CD,Schick F

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:To test the technique and feasibility of translating tumor suspicious region maps in the prostate, obtained by multimodality, anatomic, and functional 3T magnetic resonance imaging (MRI) data to 32-channel coil, T2-weighted (T2-w), 3T MR images, for directing MR-guided biopsies. Furthermore, to evaluate the ...

journal_title：Investigative radiology

authors： Hambrock T,Fütterer JJ,Huisman HJ,Hulsbergen-vandeKaa C,van Basten JP,van Oort I,Witjes JA,Barentsz JO

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVES:To investigate image quality and interstudy reproducibility of aortic atherosclerosis imaging at 1.5 T, and to explore the impact of parallel imaging techniques at 3 T. MATERIALS AND METHODS:Institutional review board approval and informed consent were obtained. Thirty-two subjects (20 normal, 12 patients w...

journal_title：Investigative radiology

authors： Maroules CD,McColl R,Khera A,Peshock RM

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:To prospectively evaluate accuracy of biliary anatomy depiction and quality of biliary tract visualization of magnetic resonance cholangiography (MRC) at 3.0 T in living potential liver donors (LPLDs). MATERIALS AND METHODS:Our institutional review board approved this study and did not require patient's inf...

journal_title：Investigative radiology

authors： Kim SY,Byun JH,Hong HS,Choi EK,Lee SS,Park SH,Lee MG

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:To quantify independent pharmacokinetic parameters for differentiation of prostate pathology. MATERIAL AND METHODS:Twenty-seven patients with biopsy-proven prostate cancer (PSA: 1.4-16.1 ng/mL) underwent magnetic resonance imaging with a new dynamic contrast-enhanced, inversion-prepared dual-contrast gradien...

journal_title：Investigative radiology

authors： Franiel T,Lüdemann L,Rudolph B,Rehbein H,Staack A,Taupitz M,Prochnow D,Beyersdorff D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:Detection of pulmonary metastases is still a challenging task for magnetic resonance imaging (MRI). It was the aim of this study to evaluate the potential of a free-breathing move-during-scan turbo inversion recovery magnitude sequence for the detection of pulmonary nodules. MATERIALS AND METHODS:The sensitivi...

journal_title：Investigative radiology

authors： Baumann T,Ludwig U,Pache G,Gall C,Saueressig U,Fisch D,Stankovic Z,Bartholomae JP,Honal M,Bley TA,Langer M,Schaefer O

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Dynamic ventilation (3)He-MRI is a new method to assess pulmonary gas inflow. As differing airway diameters throughout the ventilatory cycle can influence gas inflow this study intends to investigate the influence of volume and timing of a He gas bolus with respect to the beginning of the tidal volume on insp...

journal_title：Investigative radiology

authors： Gast KK,Hawig K,Windirsch M,Markstaller K,Schreiber WG,Schmiedeskamp J,Düber C,Kauczor HU,Heussel CP

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the potential of quantitative assays of vascular characteristics based on dynamic contrast-enhanced magnetic resonance imaging (MRI) using a macromolecular contrast medium (MMCM) to search for and measure effects of dimethyl sulfoxide (DMSO) on cancer vasculature with microscopic correlations. M...

journal_title：Investigative radiology

authors： Cyran CC,Sennino B,Chaopathomkul B,Fu Y,Rogut V,Shames DM,Wendland MF,McDonald DM,Brasch RC

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. MATERIALS AND METHODS:Twenty patients with known or suspected focal liver lesions underwent liver MRI usi...

journal_title：Investigative radiology

authors： Zech CJ,Herrmann KA,Dietrich O,Horger W,Reiser MF,Schoenberg SO

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Comparison of intravenous Fenestra VC-enhanced computed tomography (CT) with gadopentetate dimeglumine and Ferucarbotran contrast-enhanced magnetic resonance imaging (MRI) for the in vivo imaging of hepatic ischemia/reperfusion injury (IRI) in a murine model. MATERIAL AND METHODS:After induction of hepatic ...

journal_title：Investigative radiology

authors： Choukèr A,Lizak M,Schimel D,Helmberger T,Ward JM,Despres D,Kaufmann I,Bruns C,Löhe F,Ohta A,Sitkovsky MV,Klaunberg B,Thiel M

更新日期：2008-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Tools for monitoring modern target-specific antiangiogenic and antivascular therapies are highly desirable because treatment strategies are time consuming, expensive, and yet sometimes ineffective. Therefore, the aim of this experimental study was to evaluate the predictive value of steady-stat...

journal_title：Investigative radiology

authors： Persigehl T,Matuszewski L,Kessler T,Wall A,Meier N,Ebert W,Berdel WE,Heindel W,Mesters R,Bremer C

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:The incidence of coronary artery disease has been shown to be greater in patients with calcific deposits than in those without. It has been suggested that the pattern of distribution of coronary calcific deposits within coronary arteries is of greater predictive value for acute coronary events than the overa...

journal_title：Investigative radiology

authors： Wilner WT,Mazraeshahi RM,Aboshady I,Bodmann BG,Papadakis M,Kouri D,Conyers JL,Cherukuri P,Vela D,Gladish G,Gavish L,Cody DD,Frazier L,Lukovenkov S,Madjid M,Zarrabi A,Ahmed A,Willerson JT,Casscells SW,Gertz SD

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to elucidate the mechanism of hepatic parenchyma-specific contrast of Sonazoid (microbubble contrast agent) using microscopic techniques. MATERIALS AND METHODS:Sonazoid was intravenously injected into rats to investigate the microbubble dynamics and distribution within hepatic...

journal_title：Investigative radiology

authors： Watanabe R,Matsumura M,Munemasa T,Fujimaki M,Suematsu M

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a dual magnetic resonance-near infrared fluorescence optical imaging agent, poly(l-glutamic acid)-DTPA-Gd-NIR813, for both preoperative and intraoperative visualization and characterization of sentinel lymph nodes (SLN) in mice. MATERIALS AND METHODS:Poly(L-glutamic acid) was...

journal_title：Investigative radiology

authors： Melancon MP,Wang Y,Wen X,Bankson JA,Stephens LC,Jasser S,Gelovani JG,Myers JN,Li C

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of saline chase injected at 2 different rates on computed tomography (CT) angiography. MATERIALS AND METHODS:This study was approved by our institutional animal study committee. Three injection protocols were used; contrast injection (24 mL, 0.8 mL/s) without saline chase (protocol ...

journal_title：Investigative radiology

authors： Lee CH,Goo JM,Bae KT,Lee HJ,Kim KG,Chun EJ,Park CM,Im JG

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To evaluate the technical feasibility of high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) with highly accelerated parallel acquisition at 3.0 T using a 32-channel phased array coil, and a high relaxivity contrast agent. MATERIALS AND METHODS:Ten adult healthy volunteers (5 men,...

journal_title：Investigative radiology

authors： Nael K,Fenchel M,Krishnam M,Finn JP,Laub G,Ruehm SG

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To prospectively determine the accuracy of 1.5 Tesla (T) and 3 T magnetic resonance angiography (MRA) versus digital subtraction angiography (DSA) in the depiction of infrageniculate arteries in patients with symptomatic peripheral arterial disease. PATIENTS AND METHODS:A prospective 1.5 T, 3 T MRA, and DSA co...

journal_title：Investigative radiology

authors： Diehm N,Kickuth R,Baumgartner I,Srivastav SK,Gretener S,Husmann MJ,Jaccard Y,Do do D,Triller J,Bonel HM

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to assess whether fluorochrome-coupled bacterial magnetic nanoparticles can be used as bimodal contrast agent for both magnetic resonance imaging (MRI) and near-infrared fluorescence optical (NIRF) imaging of cultured macrophages. MATERIALS AND METHODS:Bacterial magnetic nanopa...

journal_title：Investigative radiology

authors： Lisy MR,Hartung A,Lang C,Schüler D,Richter W,Reichenbach JR,Kaiser WA,Hilger I

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to quantify image quality gains of a moving coronary plaque phantom using dual-source computed tomography (DSCT) providing 83 milliseconds temporal resolution in direct comparison to 64 slice single-source multidetector CT (MDCT) with a temporal resolution of 165 milliseconds. MATE...

journal_title：Investigative radiology

authors： Reimann AJ,Rinck D,Birinci-Aydogan A,Scheuering M,Burgstahler C,Schroeder S,Brodoefel H,Tsiflikas I,Herberts T,Flohr T,Claussen CD,Kopp AF,Heuschmid M

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:We sought to evaluate the influence of tube voltage on the visualization of acute myocardial infarction (MI) in cardiac multislice spiral computed tomography (MSCT). MATERIALS AND METHODS:Acute MI was induced in 12 domestic pigs by a 45-minute balloon occlusion of the left anterior descending artery. Delayed...

journal_title：Investigative radiology

authors： Mahnken AH,Bruners P,Mühlenbruch G,Emmerich M,Hohl C,Günther RW,Wildberger JE

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the diagnostic value and safety of the contrast agent gadoterate meglumine (Gd-DOTA, DOTAREM, Guerbet, Roissy CdG Cedex, France) in the setting of a postmarketing surveillance study. MATERIALS AND METHODS:Between January 2004 and October 2005, radiologists in 61 radiol...

journal_title：Investigative radiology

authors： Herborn CU,Honold E,Wolf M,Kemper J,Kinner S,Adam G,Barkhausen J

更新日期：2007-01-01 00:00:00

abstract：:Advances in the field of magnetic resonance (MR) as it pertains to clinical diagnostic radiology are examined in this review on the basis of publications in Investigative Radiology over the past 2 years (2005-2006). The articles published during that timeframe are discussed, organizationally wise, by anatomic region w...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:We sought to prospectively evaluate the image quality and visualization of the intracranial arteries using high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) at 3 T and to perform intraindividual comparison with time-of-flight (TOF) MRA and multislice CT angiography (CTA). MATERI...

journal_title：Investigative radiology

authors： Villablanca JP,Nael K,Habibi R,Nael A,Laub G,Finn JP

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. MATERIALS AND METHODS:Ten patients (4 male, 6 female; age,...

journal_title：Investigative radiology

authors： Nael K,Fenchel M,Salamon N,Duckwiler GR,Laub G,Finn JP,Villablanca JP

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Cardiac magnetic resonance imaging (MRI) at 3.0 T has recently become available and potentially provides a significant improvement of tissue contrast in T1-weighted imaging techniques relying on Gd-based contrast enhancement. Imaging at high-field strength may be especially advantageous for methods relying on...

journal_title：Investigative radiology

authors： Klumpp B,Fenchel M,Hoevelborn T,Helber U,Scheule A,Claussen C,Miller S

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:Computed tomography (CT) and magnetic resonance imaging (MRI) are introduced as an alternative to traditional autopsy. The purpose of this study was to investigate their accuracy in mass estimation of liver and spleen. METHODS:In 44 cases, the weights of spleen and liver were estimated based on MRI and CT da...

journal_title：Investigative radiology

authors： Jackowski C,Thali MJ,Buck U,Aghayev E,Sonnenschein M,Yen K,Dirnhofer R,Vock P

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Transcatheter arterial embolization (TAE) is used for the treatment of patients with malignant liver tumors. However, the proangiogenesis effect of TAE-associated hypoxia has not been adequately studied. The goal of this study was to determine angiogenic activity in tumors subjected to TAE by evaluating the ...

journal_title：Investigative radiology

authors： Gupta S,Kobayashi S,Phongkitkarun S,Broemeling LD,Kan Z

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:The aim was to investigate the feasibility and image quality of prospective respiratory gating for 3-D computed tomography (CT) of the lung. MATERIAL AND METHODS:Eight anesthetized pigs underwent prospectively gated multidetector computed tomography using 2 devices: a charge-coupled device (CCD) camera and a l...

journal_title：Investigative radiology

authors： Zaporozhan J,Ley S,Unterhinninghofen R,Saito Y,Fabel-Schulte M,Keller S,Szabo G,Kauczor HU

更新日期：2006-05-01 00:00:00

abstract：AIM:: We sought to improve the clinical interpretation of first-pass myocardial magnetic resonance perfusion. Parametric analyses of the myocardial distribution of the contrast agent have been proposed. The objective of the present study was to compare the effectiveness of visual analysis and of a parametric approach i...

journal_title：Investigative radiology

authors： Carme S,Maï W,Mazzadi A,Janier M,Revel D,Magnin I,Wiart M,Neyran B,Canet-Soulas E

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the gadolinium (Gd) concentration remaining in human bone tissue after administration of standard clinical doses of 2 Gd-based contrast agents: ProHance and Omniscan. MATERIALS AND METHODS:After administration of 0.1 mmol/kg of Gd chelate to patients undergoing hi...

journal_title：Investigative radiology

authors： White GW,Gibby WA,Tweedle MF

更新日期：2006-03-01 00:00:00

abstract：:The use of microbubble contrast agents for general tissue delineation and perfusion enjoys steady interest in ultrasound imaging. Microbubbles as contrast materials require a small dosage and show excellent detection sensitivity. Targeting ligands on the surface of microbubbles permit the selective accumulation of the...

journal_title：Investigative radiology

authors： Klibanov AL

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:Magnetic Resonance Imaging (MRI) has become the method of choice in the evaluation of patients with suspected cervical artery dissection (CAD). However, reliable identification of acute CAD might be impaired by the limited spatial resolution of standard 1.5 T MRI. In this preliminary study, we implemented a mul...

journal_title：Investigative radiology

authors： Bachmann R,Nassenstein I,Kooijman H,Dittrich R,Kugel H,Niederstadt T,Kuhlenbäumer G,Ringelstein EB,Krämer S,Heindel W

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to validate quantitation of R2* and DeltaR2* measurements obtained with a 3-dimensional (3-D) multiple gradient-recalled echo (mGRE) sequence for evaluating intrarenal oxygenation in humans. MATERIALS AND METHODS:Validation was accomplished (1) by comparing R2* values with pre...

journal_title：Investigative radiology

authors： Tumkur S,Vu A,Li L,Prasad PV

更新日期：2006-02-01 00:00:00

abstract：:In this article, we propose a semiautomatic method for time-continuous contour detection in all phases of the cardiac cycle in magnetic resonance sequences. The method is based on multidimensional dynamic programming. After shape parameterization, cost hypercubes are filled with image-feature derived cost function val...

journal_title：Investigative radiology

authors： Uzümcü M,van der Geest RJ,Swingen C,Reiber JH,Lelieveldt BP

更新日期：2006-01-01 00:00:00

abstract：:Recent publications of the magnetic resonance safety profile of neurostimulators, cardiac pacemakers, and other implanted devices imply that these devices are no longer a contraindication for magnetic resonance imaging. It is very promising that patients who have these implanted devices may in the future no longer be ...

journal_title：Investigative radiology

authors： Nitz WR,Brinker G,Diehl D,Frese G

更新日期：2005-12-01 00:00:00